Turkish Study: Prenatal Exposure to Pfizer’s COVID-19 mRNA Vaccine Induces Autism-Like Behaviors in Male Offspring
The COVID-19 pandemic catalyzed the swift development and distribution of mRNA vaccines, including BNT162b2, to address the disease. Concerns have arisen about the potential neurodevelopmental implications of these vaccines, especially in susceptible groups such as pregnant women and their offspring.
In the study, pregnant rats received the COVID-19 mRNA BNT162b2 vaccine during gestation. Subsequent evaluations on male and female offspring included autism-like behaviours, neuronal counts, and motor performance.
Findings reveal that the mRNA BNT162b2 vaccine significantly alters WNT gene expression and brain-derived neurotrophic factor (BDNF) levels in both male and female rats, suggesting a profound impact on key neurodevelopmental pathways. Notably, male rats exhibited pronounced autism-like behaviors, characterized by a marked reduction in social interaction and repetitive patterns of behavior. Furthermore, there was a substantial decrease in neuronal counts in critical brain regions, indicating potential neurodegeneration or altered neurodevelopment. Male rats also demonstrated impaired motor performance, evidenced by reduced coordination and agility.
The findings underscore the importance of continued research in this domain to guarantee the safety and well-being of all individuals, especially those who are pregnant and their offspring.
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